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Quiz 10 – Parotid Gland

Quiz 10 link

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The Two Most Common Tumors of the Parotid Gland

Normal parotid gland

Low-magnification show admixture of acinar cells within lobules, small ducts & fibroadipose tissue.

Pleomorphic Adenoma

Pleomorphic adenoma is by far the most common salivary gland tumors comprising 50%-60% of all salivary gland neoplasm and approximately 60%-80% of parotid gland neoplasm

 PAP40X

Combination of myoepithelial cells and mixoid matrix

 PAP100X

Myoepithelial cells are embedded within a pale-staining fibrillary matrix

 PAP200X

Cluster of myoepithelial cells and myxoid matrix

 MGG40X

 MGG100X

In May-Grunwald-Giemsa stain the matrix is magenta-purple

Warthin’s Tumor

Warthin’s tumor is usually cited as the second most common neoplasm and comprises 4%-14% of all salivary gland neoplasm

 PAP40X

The characteristic findings are cohesive flat sheets of oncocytes and lymphocites

 PAP100X

 PAP200X

The oncocytes have abundant densely granular cytoplasm in a background of mixed population of lymphocytes

 MGG40X

Note the absence of magenta-purple myxoid matrix