Quiz 11 – Diagnosis

Final Diagnosis:

 B) Hodgkin’s lymphoma

 Discussion:

Histology: mediastinal lymphnode excision

 h&e

 CD15

 CD30

 MUM1

 Hodgkin’s disease, is a type of lymphoma, which is a cancer originating from white blood cells called lymphocytes. Hodgkin’s lymphoma is characterized by the orderly spread of disease from one lymph node group to another and by the development of systemic symptoms with advanced disease. When Hodgkin’s cells are examined microscopically, multinucleated Reed-Sternberg cells (RS cells) are the characteristic cyto-histopathologic finding. Hodgkin’s lymphoma may be treated with radiation therapy, chemotherapy, or hematopoietic stem cell transplantation, with the choice of treatment depending on the age and sex of the patient and the stage, bulk, and histological subtype of the disease.

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