CASE N°38 – Bronchial Brushing e BAL
tac chest: smoker, multiple pulmonary nodules and enlarged lymph nodes clavicle
Cytology: Bronchial Brushing & BAL
Presence of poorly differentiated small sized malignant tumor cells, with scant/absent
cytoplasm and nuclear moulding.
Positive for malignancy. Cytological findings attributable to small cell carcinoma.
Histology: Bronchial Biopsy
Bronchial infiltration of poorly differentiated carcinoma with features related to
neuroendocrine carcinoma with small cell aspects.
Immunophenotyping: TTF1 +, CD56 +, Synaptophysin + (weak), p63–.
Proliferation index (MIB1) was approximately 60%.