CASE N°35 – Pleural effusion, Mesothelioma

Clinical History:

Age: 63

Sex: Female

Patient of 63 years. Ex smoker. dyspnea january to february 2013 for which she performed with chest X-ray evidence of left pleural effusion.
April 2013: left pleural biopsy diagnosed with malignant pleural mesothelioma. Surgical intervention. Histology: Malignant pleural mesothelioma, biphasic PT3;N2. RT radiation therapy on left hemithorax and mediastinum
March 2014 CT-SCAN Pleural effusion. Diffuse thickening with contrast enhancement at the level of the left thoracic cavity of 7 mm in the first case compatible with recurrent disease

Image:

A-H Cytological speciemen: pleural effusion (march 2014)

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Cytological Report:

Presence of many malignant tumor cells of mesothelial origin arranged in clusters and isolated, mixed with reactive mesothelial cells. Cytological findings compatible with Mesothelioma

Discussions:

In the black circles you can see the obvious malignant cells from malignant mesothelioma. In the red circles you can see reactive mesothelial cells. Make the comparison between the characteristics of the chromatin pattern to better understand the difference between reactive and malignant tumor cells.

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