CASE N°11 – Abdominal Paraganglioma
Asymptomatic. In center back peritoneum a solid para-aortic mass of approximately 6x4x5 cm was detected during TAC-SCAN. The lesion seems to be distinguished from the surrounding structures. Surgical removal was suggested.
Cytological material: EUS-FNA
Loose clusters and sometimes isolated neoplastic cells are present (histology is necessary to distinguish between benign and malignant process).
Histological material: mass excision
Paraganglioma. Immunohistochemistry coherent.
Paraganglioma is a rare neuroendocrine neoplasm that may develop at various body sites. About 85% of paragangliomas develop in the abdomen; only 12% develop in the chest and 3% in the head and neck region. Mostly (97%) are benign.
Paragangliomas are categorised as originating from a neural cell line (chromaffin cells in paraganglia or chromaffin-negative glomus cells derived from the embryonic neural crest).
Most paragangliomas are asymptomatic and present medium-big size mass. Because of size, localization and vascularization, an aortography with embolization of the nutrient branches of the tumor is suggested before surgical resection.