CASE N°10 – Submandibular Lymph node
During follow-up in autoimmune thyroiditis the echography showed Lymph node enlargement below angle of jaw, 16 mm in diameter
Cytological material: Lymph node F.N.A.
Positive for malignancy: keratinizing squamous cell carcinoma
Histological material: Lymph node excision
Keratinizing squamous cell carcinoma.
Squamous cell carcinoma is a common primary head and & neck malignant neoplasm. The risk factors (sun exposure, tobacco & alcohol) are well recognized. It is usually restricted to the mucosal surfaces of the upper aerodigestive tract and skin; in fact after our diagnosis the clinician discovered the primary site of the neoplasm that was located under the tongue.
Cytology show corneous pearls formation (fig 4) besides malignant squamous cells, sometimes with keratinazed cytoplasm (fig 1-3). Histology showed the same cell pattern.