CASE N°05 – Papillary Adenocarcinoma of Lung
Productive cough, shortness of breath and weight loss
Thorax CT: single pulmonary nodule in the lower lobe of the right lung, 2 cm in diameter
Abdominal CT: negative.The patient underwent thoracotomy for nodule excision
Cytological speciemen: Trans-Thoracic FNA
Papillary aggregates containing fibrovascular cores, lined by atypical cells with enlarged, hyperchromatic nuclei, prominent nucleoli and few intranuclear vacuoles.
Pulmonary adenocarcinoma with papillary growth pattern.
Histological material: Lung Nodule Excision
Papillary adenocarcinoma of Lung
Papillary carcinoma of the lung is a distinct clinicopathologic entity with considerably worse morbidity and mortality than bronchioloalveolar carcinoma. This unusual histopathological growth pattern is characterized by complex papillary infoldings
In most cases, areas of adenocarcinoma or bronchioloalveolar carcinoma can be identified. Pure form need to be distinguished from other types of tumours (Eg: thyroid gland or ovary).