The Two Most Common Tumors of the Parotid Gland
Normal parotid gland
Low-magnification show admixture of acinar cells within lobules, small ducts & fibroadipose tissue.
Pleomorphic adenoma is by far the most common salivary gland tumors comprising 50%-60% of all salivary gland neoplasm and approximately 60%-80% of parotid gland neoplasm
Combination of myoepithelial cells and mixoid matrix
Myoepithelial cells are embedded within a pale-staining fibrillary matrix
Cluster of myoepithelial cells and myxoid matrix
In May-Grunwald-Giemsa stain the matrix is magenta-purple
Warthin’s tumor is usually cited as the second most common neoplasm and comprises 4%-14% of all salivary gland neoplasm
The characteristic findings are cohesive flat sheets of oncocytes and lymphocites
The oncocytes have abundant densely granular cytoplasm in a background of mixed population of lymphocytes
Note the absence of magenta-purple myxoid matrix
Posted on 27/01/2012, in Parotid Gland, Pleomorphic adenoma, Warthin tumor and tagged acinar cell, major salivary gland, parotid gland, pleomorphic adenoma, warthin's tumor. Bookmark the permalink. Leave a comment.